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CALGRANULIN A
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DeCS
Descriptor
English
:
Calgranulin A
Descriptor
Spanish
:
Calgranulina A
Descriptor
Portuguese
:
Calgranulina A
Tree Number:
D12.776.157.125.750.500.100
D12.776.641.655.500.100
D23.050.301.562.100
Definition
English
:
A 10.8-kDa member of the S-100
family
of
calcium-binding proteins
that can form homo- or heterocomplexes with
CALGRANULIN B
and a variety of other
proteins
. The calgranulin A/B heterodimer is known as
LEUKOCYTE L1 ANTIGEN COMPLEX
.
Calgranulin A
is found in many cell types including
GRANULOCYTES
;
KERATINOCYTES
; and myelomonocytes, and has been shown to act as a chemotactic substance for
NEUTROPHILS
. Because it is present in acute
inflammation
but absent in chronic
inflammation
, it is a useful biological marker for a number of pathological conditions.
History Note
English
:
2003; use CALGRANULIN A (NM) 1998-2002;
Allowable Qualifiers
English
:
AD
administration & dosage
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PH
physiology
RE
radiation effects
TU
therapeutic use
UL
ultrastructure
Record Number:
37388
Unique Identifier:
D040501
Occurrence in VHL
:
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DeCS
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