Search on: CLARITHROMYCIN 
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Descriptor English:   Clarithromycin 
Descriptor Spanish:   Claritromicina 
Descriptor Portuguese:   Claritromicina 
Tree Number:   D02.540.505.250.100
Definition English:   A semisynthetic macrolide antibiotic derived from ERYTHROMYCIN that is active against a variety of microorganisms. It can inhibit protein synthesis in bacteria by reversibly binding to the 50S ribosomal subunits. This inhibits the translocation of aminoacyl transfer-RNA and prevents peptide chain elongation. 
Pharmacological Action:   Anti-Bacterial Agents
Protein Synthesis Inhibitors
 
History Note English:   93; was CLARITHROMYCIN (NM) 1987-92 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DU diagnostic use
EC economics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   30785 
Unique Identifier:   D017291 

Occurrence in VHL:
 

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