Search on: CORE BINDING FACTORS 
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Descriptor English:   Core Binding Factors 
Descriptor Spanish:   Factores de Unión al Sitio Principal 
Descriptor Portuguese:   Fatores de Ligação ao Core 
Tree Number:   D12.776.930.155
Definition English:   Heterodimeric transcription factors containing a DNA-binding alpha subunits, (CORE BINDING FACTOR ALPHA SUBUNITS), along with a non-DNA-binding beta subunits, CORE BINDING FACTOR BETA SUBUNIT. Core Binding Factor regulates GENETIC TRANSCRIPTION of a variety of GENES involved primarily in CELL DIFFERENTIATION and CELL CYCLE progression. 
Indexing Annotation English:   see SCR for organism-specific terms
History Note English:   2006(1997) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   51174 
Unique Identifier:   D050660 

Occurrence in VHL: 		 

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