Search on: CHALONES 
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Descriptor English:   Chalones 
Descriptor Spanish:   Chalonas 
Descriptor Portuguese:   Calônios 
Tree Number:   D12.644.456.270
Definition English:   Peptides that inhibit mitosis (ANTIMITOTICS). During the 1960's the term referred to crude extracts that inhibited cell proliferation; the activity was later attributed to PYROGLUTAMATE type oligopeptides. 
Indexing Annotation English:   do not confuse with CHALCONES
History Note English:   2006, 1969-1992; use GROWTH INHIBITORS 1993-2005 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   50818 
Unique Identifier:   D050150 

Occurrence in VHL:
 

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