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KALLIKREINS
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DeCS
Descriptor
English
:
Kallikreins
Descriptor
Spanish
:
Calicreínas
Descriptor
Portuguese
:
Calicreínas
Synonyms
English
:
Kininogenase
Kallikrein
Tree Number:
D08.811.277.656.300.760.442
D08.811.277.656.959.350.442
D12.776.124.125.597
D23.119.597
Definition
English
:
Proteolytic
enzymes
from the
serine
endopeptidase
family
found in normal
blood
and
urine
. Specifically,
Kallikreins
are potent vasodilators and hypotensives and increase vascular
permeability
and
affect
smooth muscle. They act as
infertility
agents in
men
. Three
forms
are recognized,
PLASMA KALLIKREIN
(EC 3.4.21.34), TISSUE KALLIKREIN (EC 3.4.21.35), and
PROSTATE-SPECIFIC ANTIGEN
(EC 3.4.21.77).
Indexing Annotation
English
:
/antag permitted but consider KALLIKREIN-TRYPSIN INACTIVATOR
Pharmacological Action:
Coagulants
Fertility Agents, Male
See Related
English
:
Coagulants
History Note
English
:
2000(1963)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
23326
Unique Identifier:
D007610
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS