Search on: KERATIN-2 
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Descriptor English:   Keratin-2 
Descriptor Spanish:   Queratina-2 
Descriptor Portuguese:   Queratina-2 
Tree Number:   D05.750.078.593.450.600.200
D12.776.220.475.450.600.200
D12.776.860.607.650.200
Definition English:   A type II keratin found expressed in the upper spinous layer of epidermal KERATINOCYTES. Mutations in genes that encode keratin-2A have been associated with ICHTHYOSIS BULLOSA OF SIEMENS. 
History Note English:   2007 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   52195 
Unique Identifier:   D053557 

Occurrence in VHL:
 

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