Pesquisa sobre:
RECEPTORS, DEATH DOMAIN
Descritores Encontrados:
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DeCS
Descritor
Inglês
:
Receptors, Death Domain
Descritor
Espanhol
:
Receptores de Muerte Celular
Descritor
Português
:
Receptores de Morte Celular
Sinônimos
Inglês
:
Death Domain Receptors
Categoria:
D12.776.543.750.073
Definição
Inglês
:
A
family
of cell surface receptors that signal via a conserved domain that extends into the cell
CYTOPLASM
. The conserved domain is referred to as a
death
domain due to the fact that many of these receptors are involved in signaling
APOPTOSIS
. Several
DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS
can bind to the
death
domains of the activated receptors and through a complex series of interactions activate apoptotic mediators such as
CASPASES.
Relacionados
Inglês
:
Receptors, Tumor Necrosis Factor
Nota Histórica
Inglês
:
2007
Qualificadores Permitidos
Inglês
:
AD
administration & dosage
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PH
physiology
RE
radiation effects
TU
therapeutic use
UL
ultrastructure
Número do Registro:
52336
Identificador Único:
D053218
Ocorrência na BVS
:
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