Search on: CATHEPSIN B 
Descriptors Found: 1
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Descriptor English:   Cathepsin B 
Descriptor Spanish:   Catepsina B 
Descriptor Portuguese:   Catepsina B 
Tree Number:   D08.811.277.656.224.125
D08.811.277.656.262.500.133
D08.811.277.656.300.200.133
Definition English:   A lysosomal cysteine proteinase with a specificity similar to that of PAPAIN. The enzyme is present in a variety of tissues and is important in many physiological and pathological processes. In pathology, cathepsin B has been found to be involved in DEMYELINATION; EMPHYSEMA; RHEUMATOID ARTHRITIS, and NEOPLASM INVASIVENESS. 
History Note English:   87 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   23222 
Unique Identifier:   D002401 

Occurrence in VHL:
 

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