Search on: CLEAVAGE STIMULATION FACTOR 
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Descriptor English:   Cleavage Stimulation Factor 
Descriptor Spanish:   Factor de Estimulación del Desdoblamiento 
Descriptor Portuguese:   Fator Estimulador de Clivagem 
Tree Number:   D12.776.157.725.124.249
D12.776.664.962.444.249
Definition English:   A RNA-binding protein that stimulates the cleavage of the 3' end of MRNA near the POLYADENYLATION site. It is a heterotrimer of 55-, 64- and 77-kDa subunits and combines with CLEAVAGE STIMULATION FACTOR to form a stable complex with mRNA that directs the 3' cleavage and polyadenylation reaction. 
History Note English:   2003; for CLEAVAGE STIMULATION FACTOR use MRNA CLEAVAGE AND POLYADENYLATION FACTORS (NM) 1992-2002 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   37404 
Unique Identifier:   D039241 

Occurrence in VHL:
 

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