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EUKARYOTIC INITIATION FACTOR-5
Descriptors Found:
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DeCS
Descriptor
English
:
Eukaryotic Initiation Factor-5
Descriptor
Spanish
:
Factor 5 Eucariótico de Iniciación
Descriptor
Portuguese
:
Fator de Iniciação 5 em Eucariotos
Synonyms
English
:
EIF-5
Peptide Initiation Factor EIF-5
Tree Number:
D12.644.360.325.150.300
D12.776.402.150.300
D12.776.476.325.150.300
D12.776.835.725.868.750
Definition
English
:
A eukaryotic initiation factor that interacts with the 40S initiation complex and promotes the
hydrolysis
of the bound GTP. The
hydrolysis
of GTP causes the release of
EUKARYOTIC INITIATION FACTOR-2
and
EUKARYOTIC INITIATION FACTOR-3
from the 40S subunit and the subsequent joining of the 60S ribosomal subunit to the 40S complex to form the functional 80S initiation complex
Pharmacological Action:
GTP Phosphohydrolase Activators
History Note
English
:
2003; use EUKARYOTIC INITIATION FACTOR-5 (NM) 1982-2002
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
37453
Unique Identifier:
D040061
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS