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FIBRIN SEALANT SYSTEM
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DeCS
Descriptor
English
:
Fibrin Tissue Adhesive
Descriptor
Spanish
:
Adhesivo de Tejido de Fibrina
Descriptor
Portuguese
:
Adesivo Tecidual de Fibrina
Synonyms
English
:
Autologous Fibrin Tissue Adhesive
Fibrin Adhesive
Fibrin Glue
Fibrin Sealant System
Fibrinogen Adhesive
Tree Number:
D12.776.124.270.305
Definition
English
:
An autologous or commercial tissue adhesive containing
FIBRINOGEN
and
THROMBIN
. The commercial product is a two component system from human
plasma
that contains more than
fibrinogen
and
thrombin
. The first component contains highly concentrated
fibrinogen
,
FACTOR VIII
, fibronectin, and traces of other
plasma
proteins
. The second component contains
thrombin
,
calcium chloride
, and
antifibrinolytic agents
such as
APROTININ
. Mixing of the two components promotes
BLOOD
CLOTTING and the formation and cross-linking of
fibrin
. The tissue adhesive is used for tissue sealing,
HEMOSTASIS
, and
WOUND HEALING.
Pharmacological Action:
Hemostatics
Tissue Adhesives
History Note
English
:
90
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DU
diagnostic use
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
24653
Unique Identifier:
D015718
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS