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DeCS
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Descriptor English:
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Genes, erbA
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Descriptor Spanish:
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Genes erbA
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Descriptor Portuguese:
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Genes erbA
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Synonyms English:
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c-erbA Genes
erbA Genes
v-erbA Genes
Genes, erbA-alpha
Genes, erbA-beta
Genes, TR-alpha
Genes, TR-beta
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Tree Number:
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G05.360.340.024.340.375.500.791.290
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Definition English:
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Genes related to the erbA DNA sequence that was first isolated from the avian erythroblastosis virus (ERYTHROBLASTOSIS VIRUS, AVIAN), v-erbA. In cells, erbA genes encode thyroid hormone receptors (RECEPTORS, THYROID HORMONE). Two distinct c-erbA genes have been identified: erbA-alpha located at 17q21; and erbA-beta located at 3p24. Truncations at the N- and C-terminals of erbA result in products resembling v-erbA. Truncations affect hormone responsiveness but not DNA binding capacity. |
Indexing Annotation English:
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erbA stands for "ERythroBlastosis virus, Avian"; GENES, ERBB & its specifics are also available; in titles & translations spell as erbA
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See Related English:
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Oncogene Proteins v-erbA
Receptors, Thyroid Hormone
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History Note English:
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95
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Allowable Qualifiers English:
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Record Number:
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32229
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Unique Identifier:
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D018776
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Occurrence in VHL:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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