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DeCS
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Descriptor English:
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Histamine H1 Antagonists, Non-Sedating
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Descriptor Spanish:
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Antagonistas de los Receptores Histamínicos H1 no Sedantes
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Descriptor Portuguese:
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Antagonistas dos Receptores Histamínicos H1 não Sedativos
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Tree Number:
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D27.505.519.625.375.425.400.500
D27.505.696.577.375.425.400.500
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Definition English:
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A class of non-sedating drugs that bind to but do not activate histamine receptors (DRUG INVERSE AGONISM), thereby blocking the actions of histamine or histamine agonists. These antihistamines represent a heterogenous group of compounds with differing chemical structures, adverse effects, distribution, and metabolism. Compared to the early (first generation) antihistamines, these non-sedating antihistamines have greater receptor specificity, lower penetration of BLOOD-BRAIN BARRIER, and are less likely to cause drowsiness or psychomotor impairment. |
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See Related English:
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Anti-Allergic Agents
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History Note English:
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2003
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Allowable Qualifiers English:
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Record Number:
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37547
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Unique Identifier:
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D039563
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Occurrence in VHL:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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