Search on: HYDROXYMETHYLGLUTARYL-COA SYNTHASE 
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Descriptor English:   Hydroxymethylglutaryl-CoA Synthase 
Descriptor Spanish:   Hidroximetilglutaril-CoA Sintasa 
Descriptor Portuguese:   Hidroximetilglutaril-CoA Sintase 
Tree Number:   D08.811.913.050.612
Definition English:   An enzyme that catalyzes the synthesis of hydroxymethylglutaryl-CoA from acetyl-CoA and acetoacetyl-CoA. This is a key enzyme in steroid biosynthesis. This enzyme was formerly listed as EC 4.1.3.5. 
Indexing Annotation English:   DF: HMG COA SYNTHASE
History Note English:   1991(1975); 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   7075 
Unique Identifier:   D006904 

Occurrence in VHL:
 

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