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MAJOR BASIC PROTEIN, EOSINOPHIL
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DeCS
Descriptor
English
:
Eosinophil Major Basic Protein
Descriptor
Spanish
:
Proteina Mayor Básica del Eosinófilo
Descriptor
Portuguese
:
Proteína Básica Maior de Eosinófilos
Synonyms
English
:
Eosinophil Basic Protein
Major Basic Protein, Eosinophil
Tree Number:
D12.776.124.486.379.500
Definition
English
:
One of several basic
proteins
released from EOSINOPHIL
cytoplasmic granules
.
Eosinophil major basic protein
is a 14-kDa cytotoxic peptide with a pI of 10.9. In addition to its direct cytotoxic effects, it stimulates the release of variety of
INFLAMMATION MEDIATORS.
Pharmacological Action:
Immunologic Factors
History Note
English
:
2005(1981)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
38755
Unique Identifier:
D047093
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS