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MEDPHALAN
Descriptors Found:
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DeCS
Descriptor
English
:
Melphalan
Descriptor
Spanish
:
Melfalán
Descriptor
Portuguese
:
Melfalan
Synonyms
English
:
Medphalan
Merphalan
Phenylalanine Mustard
Sarcolysine
Sarkolysin
Tree Number:
D02.455.526.728.650.594
D12.125.072.050.685.500
Definition
English
:
An alkylating
nitrogen
mustard that is used as an antineoplastic in the form of the levo isomer -
MELPHALAN
, the racemic mixture - MERPHALAN, and the dextro isomer - MEDPHALAN; toxic to
bone marrow
, but little vesicant action; potential carcinogen.
Pharmacological Action:
Antineoplastic Agents, Alkylating
Myeloablative Agonists
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DU
diagnostic use
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
8727
Unique Identifier:
D008558
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS