Search on: PROKARYOTIC INITIATION FACTOR-1 
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Descriptor English:   Prokaryotic Initiation Factor-1 
Descriptor Spanish:   Factor 1 Procariótico de Iniciación 
Descriptor Portuguese:   Fator de Iniciação 1 em Procariotos 
Synonyms English:   Peptide Initiation Factor IF-1  
Tree Number:   D12.776.835.725.934.374
Definition English:   The smallest of the three prokaryotic initiation factors with a molecular size of approximately 8 kD. It binds near the A-site of the 30S subunit of RIBOSOMES and may play a role in preventing premature addition of aminoacyl-tRNA-linked PEPTIDE ELONGATION FACTOR TU to the ribosome during the initiation of a peptide chain (PEPTIDE CHAIN INITIATION, TRANSLATIONAL). 
History Note English:   2003; for IF-1 use EUKARYOTIC INITIATION FACTOR-1 1990-2002 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   37529 
Unique Identifier:   D039861 

Occurrence in VHL:
 

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