Search on: PROKARYOTIC INITIATION FACTOR-2 
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Descriptor English:   Prokaryotic Initiation Factor-2 
Descriptor Spanish:   Factor 2 Procariótico de Iniciación 
Descriptor Portuguese:   Fator de Iniciação 2 em Procariotos 
Synonyms English:   Peptide Initiation Factor IF-2  
Tree Number:   D12.776.835.725.934.562
Definition English:   The largest of the three prokaryotic initiation factors with a molecular size of approximately 80 kD. It functions in the transcription initiation process by promoting the binding of formylmethionine-tRNA to the P-site of the 30S ribosome and by preventing the incorrect binding of elongator tRNA to the translation initiation site. 
History Note English:   2003; use PROKARYOTIC INITIATION FACTOR-2 (NM) 1990-2002 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   37530 
Unique Identifier:   D039881 

Occurrence in VHL:
 

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