Search on: PULMONARY SURFACTANT-ASSOCIATED PROTEIN A 
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Descriptor English:   Pulmonary Surfactant-Associated Protein A 
Descriptor Spanish:   Proteína A Asociada a Surfactante Pulmonar 
Descriptor Portuguese:   Proteína A Associada a Surfactante Pulmonar 
Tree Number:   D12.776.503.280.249.600
D12.776.823.100
Definition English:   An abundant pulmonary surfactant-associated protein that binds to a variety of lung pathogens, resulting in their opsinization. It also stimulates MACROPHAGES to undergo PHAGOCYTOSIS of microorganisms. Surfactant protein A contains a N-terminal collagen-like domain and a C-terminal lectin domain that are characteristic of members of the collectin family of proteins. 
Indexing Annotation English:   see SCR for species-specific terms; DF: SP-A PROTEIN
Pharmacological Action:   Pulmonary Surfactants
 
History Note English:   2003; for SURFACTANT PROTEIN A & SP-A PROTEIN use PULMONARY SURFACTANT-ASSOCIATED PROTEINS (NM) 1991-2002 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   37462 
Unique Identifier:   D037662 

Occurrence in VHL:
 

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