Search on: PULMONARY SURFACTANT-ASSOCIATED PROTEIN C 
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Descriptor English:   Pulmonary Surfactant-Associated Protein C 
Descriptor Spanish:   Proteína C Asociada a Surfactante Pulmonar 
Descriptor Portuguese:   Proteína C Associada a Surfactante Pulmonar 
Synonyms English:   Pulmonary Surfactant-Associated Protein SP-C  
Tree Number:   D12.776.543.717
D12.776.816.750
D12.776.823.186
Definition English:   A pulmonary surfactant associated protein that plays a role in alveolar stability by lowering the surface tension at the air-liquid interface. It is a membrane-bound protein that constitutes 1-2% of the pulmonary surfactant mass. Pulmonary surfactant-associated protein C is one of the most hydrophobic peptides yet isolated and contains an alpha-helical domain with a central poly-valine segment that binds to phospholipid bilayers. 
Indexing Annotation English:   DF: SP-C PROTEIN
Pharmacological Action:   Pulmonary Surfactants
 
History Note English:   2003; use PULMONARY SURFACTANT-ASSOCIATED PROTEIN C (NM) 1990-2002 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   37474 
Unique Identifier:   D037721 

Occurrence in VHL:
 

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