Search on:
RNA TRANS-SPLICING
Descriptors Found:
1
Displaying:
1 .. 1
1 / 1
DeCS
Descriptor
English
:
Trans-Splicing
Descriptor
Spanish
:
Trans-Empalme
Descriptor
Portuguese
:
Trans-Splicing
Synonyms
English
:
RNA Trans-Splicing
Trans RNA Splicing
Tree Number:
G02.111.087.750.700.750
G02.149.115.750.700.750
G03.495.839.700.750
G05.355.315.700.700.750
Definition
English
:
The joining of
RNA
from two different
genes
. One type of
trans-splicing
is the "spliced leader" type (primarily found in protozoans such as trypanosomes and in lower
invertebrates
such as nematodes) which results in the addition of a capped, noncoding, spliced leader sequence to the 5' end of mRNAs. Another type of
trans-splicing
is the "discontinuous group II introns" type (found in plant/algal
chloroplasts
and plant
mitochondria
) which results in the joining of two independently transcribed coding sequences. Both are mechanistically
similar
to conventional nuclear pre-mRNA cis-splicing. Mammalian
cells
are also capable of
trans-splicing.
Indexing Annotation
English
:
note category: a physiol process taking place within the
cell nucleus
; do not confuse with
DNA
, RECOMBINANT; CLONING, MOLECULAR; or
GENETIC ENGINEERING
See Related
English
:
RNA, Spliced Leader
History Note
English
:
99
Allowable Qualifiers
English
:
DE
drug effects
ES
ethics
GE
genetics
IM
immunology
PH
physiology
RE
radiation effects
Record Number:
33898
Unique Identifier:
D020040
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS