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RECEPTORS, NEUROKININ-1
Descriptors Found:
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DeCS
Descriptor
English
:
Receptors, Neurokinin-1
Descriptor
Spanish
:
Receptores de Neuroquinina-1
Descriptor
Portuguese
:
Receptores da Neurocinina-1
Synonyms
English
:
Neurokinin-1 Receptors
NK-1 Receptors
Receptors, Substance P
Substance P Receptors
SP-P Receptors
Tree Number:
D12.776.543.750.100.862.500
D12.776.543.750.720.600.830.500
D12.776.543.750.750.555.830.500
Definition
English
:
A class of cell surface receptors for
TACHYKININS
with a preference for
SUBSTANCE P
. Neurokinin-1 (NK-1) receptors have been cloned and are members of the G protein coupled receptor superfamily. They are found on many cell types including central and peripheral
neurons
, smooth
muscle cells
,
acinar cells
,
endothelial cells
,
fibroblasts
, and immune
cells.
Entry Combination - descr/qualif
English
:
Receptors, Neurokinin-1
/
antagonists & inhibitors
use
Neurokinin-1 Receptor Antagonists
History Note
English
:
94; was SUBSTANCE P RECEPTOR (NM) 1981-93; NK-1 RECEPTOR & NEUROKININ-1 RECEPTOR were SY to SUBSTANCE K RECEPTOR 1986-93; NK-1 RECEPTOR SITE was SY to TACHYKININ RECEPTOR 1989-93
Allowable Qualifiers
English
:
AD
administration & dosage
AG
agonists
AN
analysis
BI
biosynthesis
BL
blood
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PH
physiology
RE
radiation effects
TU
therapeutic use
UL
ultrastructure
Record Number:
31113
Unique Identifier:
D018040
Occurrence in VHL
:
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