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RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR
Descriptors Found:
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DeCS
Descriptor
English
:
Receptors, Vascular Endothelial Growth Factor
Descriptor
Spanish
:
Receptores de Factores de Crecimiento Endotelial Vascular
Descriptor
Portuguese
:
Receptores de Fatores de Crescimento do Endotélio Vascular
Tree Number:
D08.811.913.696.620.682.725.400.950
D12.776.543.750.060.750
D12.776.543.750.750.400.910
Definition
English
:
A
family
of closely related
RECEPTOR PROTEIN-TYROSINE KINASES
that bind
vascular endothelial growth factors
. They share a cluster of seven extracellular Ig-like domains which are important for ligand binding. They are highly expressed in vascular
endothelial cells
and are critical for the physiological and pathological
growth
, development and
maintenance
of
blood
and
lymphatic vessels.
Indexing Annotation
English
:
GEN; prefer specifics, DF: VEGF RECEPT
History Note
English
:
2003; use RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR (NM) 1991-2002; for ENDOTHELIAL GROWTH FACTOR RECEPTOR use RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR (NM) 1985-2003
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
37357
Unique Identifier:
D040262
Occurrence in VHL
:
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