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SEMAPHORIN-3A
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DeCS
Descriptor
English
:
Semaphorin-3A
Descriptor
Spanish
:
Semaforina-3A
Descriptor
Portuguese
:
Semaforina-3A
Tree Number:
D12.644.276.923.374
D12.776.467.923.374
D23.529.923.374
Definition
English
:
The prototypical and most well-studied member of the semaphorin
family
.
Semaphorin-3A
is an axon-repulsive guidance cue for migrating
neurons
in the developing
nervous system
. It has so far been found only in
vertebrates
, and binds to NEUROPILIN-1/plexin complex receptors on
growth cones
. Like other class 3
semaphorins
, it is a secreted protein.
History Note
English
:
2003; use SEMAPHORIN 3A (NM) 1994-2002
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
37455
Unique Identifier:
D040121
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS