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TESTOSTERONE-ESTRADIOL BINDING GLOBULIN
Descriptors Found:
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DeCS
Descriptor
English
:
Sex Hormone-Binding Globulin
Descriptor
Spanish
:
Globulina de Unión a Hormona Sexual
Descriptor
Portuguese
:
Globulina de Ligação a Hormônio Sexual
Synonyms
English
:
Testosterone-Estradiol Binding Globulin
Sex Steroid-Binding Protein
Tree Number:
D12.776.124.790.223.800
D12.776.157.762
D12.776.377.715.182.800
Definition
English
:
A glycoprotein migrating as a beta-globulin. Its
molecular weight
, 52,000 or 95,000-115,000, indicates that it exists as a dimer. The protein binds
testosterone
,
dihydrotestosterone
, and
estradiol
in the
plasma
.
Sex
hormone-binding protein has the same
amino acid sequence
as
ANDROGEN-BINDING PROTEIN
. They differ by their sites of synthesis and post-translational oligosaccharide modifications.
Indexing Annotation
English
:
does not refer to all
sex
hormones
: refers to a specific protein in the
blood
binding only
testosterone
or
estradiol
; for other
sex
hormone-binding
globulins
consider
ANDROGEN-BINDING PROTEIN
&
PROGESTERONE-BINDING GLOBULIN
; DF: SHBG
See Related
English
:
Androgen-Binding Protein
History Note
English
:
77; SEX STEROID-BINDING PROTEIN was SEX-STEROID-BINDING PROTEIN (NM) 1981-91; ESTRADIOL-BINDING GLOBULIN & TESTOSTERONE-BINDING GLOBULIN were see SEX HORMONE-BINDING GLOBULIN 1977-92
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
22292
Unique Identifier:
D012738
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
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