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THYROID HORMONE RECEPTORS BETA
Descriptors Found:
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DeCS
Descriptor
English
:
Thyroid Hormone Receptors beta
Descriptor
Spanish
:
Receptores beta de Hormona Tiroidea
Descriptor
Portuguese
:
Receptores beta dos Hormônios Tireóideos
Synonyms
English
:
Receptors beta, Thyroid Hormone
Tree Number:
D12.776.260.698.850.750
D12.776.624.664.700.830.750
D12.776.826.850.750
D12.776.930.669.850.750
Definition
English
:
High affinity receptors for
THYROID HORMONES
, especially
TRIIODOTHYRONINE
. These receptors are usually found in the nucleus where they regulate
DNA
transcription. They are encoded by the THRB gene (also known as NR1A2, THRB1, or ERBA2 gene) as several isoforms produced by
alternative splicing
. Mutations in the THRB gene cause
THYROID HORMONE RESISTANCE SYNDROME.
History Note
English
:
2003; use RECEPTORS, THYROID HORMONE 1994-2002
Allowable Qualifiers
English
:
AD
administration & dosage
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PH
physiology
RE
radiation effects
TU
therapeutic use
UL
ultrastructure
Record Number:
37517
Unique Identifier:
D037042
Occurrence in VHL
:
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