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TUFTSIN
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DeCS
Descriptor
English
:
Tuftsin
Descriptor
Spanish
:
Tuftsina
Descriptor
Portuguese
:
Tuftsina
Tree Number:
D12.644.456.840
D12.644.541.500.650.750
D12.776.124.486.485.397.500
D12.776.124.486.485.680.650.750
D12.776.124.790.651.397.500
D12.776.124.790.651.680.650.750
D12.776.377.715.548.397.500
D12.776.377.715.548.680.650.750
Definition
English
:
N(2)-((1-(N(2)-L-Threonyl)-L-lysyl)-L-prolyl)-L-arginine. A tetrapeptide produced in the
spleen
by enzymatic cleavage of a leukophilic gamma-globulin. It stimulates the phagocytic activity of
blood
polymorphonuclear
leukocytes
and
neutrophils
in particular. The peptide is located in the Fd fragment of the gamma-globulin molecule.
Pharmacological Action:
Immunologic Factors
History Note
English
:
84(75); was see under IMMUNOGLOBULINS, FD 1975-83; LEUKOKININ (with LEUCOKININ a see ref to it) was see under GAMMA GLOBULINS 1975-83; LEUKOKININ & LEUCOKININ were see TUFTSIN 1984-93
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
14807
Unique Identifier:
D014405
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS