|
1 / 1
|
DeCS
|
|
 |
|
Descriptor English:
|
|
Proto-Oncogene Proteins c-abl
|
|
Descriptor Spanish:
|
|
Proteínas Proto-Oncogénicas c-abl
|
|
Descriptor Portuguese:
|
|
Proteínas Proto-Oncogênicas c-abl
|
|
Synonyms English:
|
|
c-abl Proteins
abl Proto-Oncogene Proteins
|
|
Tree Number:
|
|
D08.811.913.696.620.682.725.500
D12.776.624.664.700.167
|
|
Definition English:
|
|
Non-receptor tyrosine kinases encoded by the C-ABL GENES. They are distributed in both the cytoplasm and the nucleus. c-Abl plays a role in normal HEMATOPOIESIS especially of the myeloid lineage. Oncogenic transformation of c-abl arises when specific N-terminal amino acids are deleted, releasing the kinase from negative regulation. |
|
See Related English:
|
|
Fusion Proteins, bcr-abl
|
|
History Note English:
|
|
91
|
|
Allowable Qualifiers English:
|
|
|
|
Record Number:
|
|
29092
|
|
Unique Identifier:
|
|
D016315
|
Occurrence in VHL:
|
|
|
Similar:
|
|
DeCS CID-10 SciELO LILACS LIS
|