Search on: INTERLEUKIN-18 
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Descriptor English:   Interleukin-18 
Descriptor Spanish:   Interleucina-18 
Descriptor Portuguese:   Interleucina-18 
Synonyms English:   Interferon-gamma-Inducing Factor
IFN-gamma-Inducing Factor
IL-18  
Tree Number:   D12.644.276.374.465.518
D12.776.467.374.465.518
D23.529.374.465.518
Definition English:   A cytokine which resembles IL-1 structurally and IL-12 functionally. It enhances the cytotoxic activity of NK CELLS and CYTOTOXIC T-LYMPHOCYTES, and appears to play a role both as neuroimmunomodulator and in the induction of mucosal immunity. 
Indexing Annotation English:   DF: IL18
History Note English:   99; use INTERLEUKIN-18 (NM) 1995-98 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   33854 
Unique Identifier:   D020382 

Occurrence in VHL:
 

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