Search on: INTERLEUKIN-4 
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Descriptor English:   Interleukin-4 
Descriptor Spanish:   Interleucina-4 
Descriptor Portuguese:   Interleucina-4 
Synonyms English:   B-Cell Stimulatory Factor-1
IL-4
Mast Cell Growth Factor-2
B-Cell Growth Factor-I
Binetrakin  
Tree Number:   D12.644.276.374.465.504
D12.776.467.374.465.504
D23.529.374.465.504
Definition English:   A soluble factor produced by activated T-LYMPHOCYTES that induces the expression of MHC CLASS II GENES and FC RECEPTORS on B-LYMPHOCYTES and causes their proliferation and differentiation. It also acts on T-lymphocytes, MAST CELLS, and several other hematopoietic lineage cells. 
Indexing Annotation English:   DF: IL 4 or IL4
Pharmacological Action:   Adjuvants, Immunologic
Antineoplastic Agents
Antirheumatic Agents
 
See Related English:   Histocompatibility Antigens Class II
 
History Note English:   90; B-CELL GROWTH FACTOR was see INTERLEUKIN-4 1990-96 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   29470 
Unique Identifier:   D015847 

Occurrence in VHL:
 

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