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ADRENOMEDULLIN
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DeCS
Descriptor
English
:
Adrenomedullin
Descriptor
Spanish
:
Adrenomedulina
Descriptor
Portuguese
:
Adrenomedulina
Tree Number:
D06.472.699.077
D12.644.548.017
Definition
English
:
A 52-amino acid peptide with multi-functions. It was originally isolated from
PHEOCHROMOCYTOMA
and
ADRENAL MEDULLA
but is widely distributed throughout the body including
lung
and
kidney
tissues
. Besides controlling fluid-electrolyte
homeostasis
,
adrenomedullin
is a potent vasodilator and can inhibit pituitary ACTH secretion.
Pharmacological Action:
Antihypertensive Agents
Bronchodilator Agents
Cardiotonic Agents
Vasodilator Agents
History Note
English
:
2007 (1993)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
52207
Unique Identifier:
D053607
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS