Search on: APOPROTEIN(A) 
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Descriptor English:   Apoprotein(a) 
Descriptor Spanish:   Apoproteína(a) 
Descriptor Portuguese:   Apoproteína(a) 
Synonyms English:   Apolipoprotein Lp(a)  
Tree Number:   D10.532.350.500
D12.776.521.400.500
Definition English:   A large and highly glycosylated protein constituent of LIPOPROTEIN (A). It has very little affinity for lipids but forms disulfide-linkage to APOLIPOPROTEIN B-100. Apoprotein(a) has SERINE PROTEINASE activity and can be of varying sizes from 400- to 800-kDa. It is homologous to PLASMINOGEN and is known to modulate THROMBOSIS and FIBRINOLYSIS. 
Indexing Annotation English:   do not confuse with APOLIPOPROTEINS A, normal structural proteins of the alpha-lipoproteins (HIGH DENSITY LIPOPROTEINS)
History Note English:   2007 (1986); use APOLIPOPROTEINS A 1988-2006 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   52270 
Unique Identifier:   D053241 

Occurrence in VHL:
 

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