Search on: SCLEROMYXEDEMA 
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Descriptor English:   Scleromyxedema 
Descriptor Spanish:   Escleromixedema 
Descriptor Portuguese:   Escleromixedema 
Synonyms English:   Lichen Myxedematosus
Papular Mucinosis  
Tree Number:   C17.300.550.875
Definition English:   A connective tissue disorder characterized by widespread thickening of SKIN with a cobblestone-like appearance. It is caused by proliferation of FIBROBLASTS and deposition of MUCIN in the DERMIS in the absence of thyroid disease. Most scleromyxedema cases are associated with a MONOCLONAL GAMMOPATHY, immunoglobulin IgG-lambda. 
See Related English:   Myxedema
 
History Note English:   2007 
Allowable Qualifiers English:  
BL blood CF cerebrospinal fluid
CI chemically induced CL classification
CO complications CN congenital
DI diagnosis DH diet therapy
DT drug therapy EC economics
EM embryology EN enzymology
EP epidemiology EH ethnology
ET etiology GE genetics
HI history IM immunology
ME metabolism MI microbiology
MO mortality NU nursing
PS parasitology PA pathology
PP physiopathology PC prevention & control
PX psychology RA radiography
RI radionuclide imaging RT radiotherapy
RH rehabilitation SU surgery
TH therapy US ultrasonography
UR urine VE veterinary
VI virology  
Record Number:   52148 
Unique Identifier:   D053718 

Occurrence in VHL:
 

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