Search on: UROGASTRONE 
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Descriptor English:   Epidermal Growth Factor 
Descriptor Spanish:   Factor de Crecimiento Epidérmico 
Descriptor Portuguese:   Fator de Crescimento Epidérmico 
Synonyms English:   Epidermal Growth Factor-Urogastrone
Urogastrone
EGF  
Tree Number:   D06.472.317.350
D12.644.276.561
D12.776.467.561
D23.529.561
Definition English:   A 6-kDa polypeptide growth factor initially discovered in mouse submaxillary glands. Human epidermal growth factor was originally isolated from urine based on its ability to inhibit gastric secretion and called urogastrone. EPIDERMAL GROWTH FACTOR exerts a wide variety of biological effects including the promotion of proliferation and differentiation of mesenchymal and epithelial cells. 
See Related English:   Anti-Ulcer Agents
Gastrointestinal Agents
Receptor, Epidermal Growth Factor
 
History Note English:   2000(1982); use PEPTIDES 1977-1981; for UROGASTRONE use GASTROINTESTINAL HORMONES 1963-1981 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   4896 
Unique Identifier:   D004815 

Occurrence in VHL:
 

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