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UROPORPHYRINOGENS
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DeCS
Descriptor
English
:
Uroporphyrinogens
Descriptor
Spanish
:
Uroporfirinógenos
Descriptor
Portuguese
:
Uroporfirinogênios
Tree Number:
D03.383.129.578.840.500.700.900
D03.549.909.500.700.900
D04.345.783.500.700.900
Definition
English
:
Porphyrinogens
which are intermediates in
heme
biosynthesis. They have four
acetic acid
and four propionic acid side chains attached to the pyrrole rings. Uroporphyrinogen I and III are formed from polypyrryl
methane
in the presence of uroporphyrinogen III cosynthetase and uroporphyrin I synthetase, respectively. They can yield
uroporphyrins
by autooxidation or
coproporphyrinogens
by
decarboxylation.
Indexing Annotation
English
:
porphyrins
History Note
English
:
91(76); was see under PORPHYRINOGENS 1976-90
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
14979
Unique Identifier:
D014577
Occurrence in VHL
:
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