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PREKALLIKREIN
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DeCS
Descriptor
English
:
Prekallikrein
Descriptor
Spanish
:
Precalicreína
Descriptor
Portuguese
:
Pré-Calicreína
Synonyms
English
:
Fletcher Factor
Plasma Prokallikrein
Tree Number:
D08.811.277.656.300.760.442.725
D08.811.277.656.959.350.442.725
D12.776.124.125.597.712
D23.119.597.712
Definition
English
:
A
plasma
protein which is the precursor of kallikrein.
Plasma
that is deficient in
prekallikrein
has been found to be abnormal in
thromboplastin
formation, kinin generation, evolution of a
permeability
globulin, and plasmin formation. The absence of
prekallikrein
in
plasma
leads to Fletcher factor deficiency, a congenital
disease.
See Related
English
:
Coagulants
History Note
English
:
89(76); was see under KALLIKREINS 1976-88
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
22264
Unique Identifier:
D011288
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS