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PROTHROMBIN
Descriptors Found:
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DeCS
Descriptor
English
:
Prothrombin
Descriptor
Spanish
:
Protrombina
Descriptor
Portuguese
:
Protrombina
Synonyms
English
:
Factor II
Coagulation Factor II
Tree Number:
D08.622.709
D12.776.124.125.800
D23.119.945
Definition
English
:
A
plasma
protein that is the inactive precursor of
thrombin
. It is converted to
thrombin
by a
prothrombin
activator complex consisting of
factor Xa
,
factor V
, phospholipid, and
calcium
ions
. Deficiency of
prothrombin
leads to hypoprothrombinemia.
Indexing Annotation
English
:
a
blood
coag factor; an enzyme precursor
Entry Combination - descr/qualif
English
:
Prothrombin
/
deficiency
use
Hypoprothrombinemias
See Related
English
:
Coagulants
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
22270
Unique Identifier:
D011516
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS