Search on: INTERLEUKIN-11 
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Descriptor English:   Interleukin-11 
Descriptor Spanish:   Interleucina-11 
Descriptor Portuguese:   Interleucina-11 
Synonyms English:   Adipogenesis Inhibitory Factor
IL-11  
Tree Number:   D12.644.276.374.465.511
D12.776.467.374.465.511
D23.529.374.465.511
Definition English:   A lymphohematopoietic cytokine that plays a role in regulating the proliferation of ERYTHROID PRECURSOR CELLS. It induces maturation of MEGAKARYOCYTES which results in increased production of BLOOD PLATELETS. Interleukin-11 was also initially described as an inhibitor of ADIPOGENESIS of cultured preadipocytes. 
Indexing Annotation English:   DF: IL 11 or IL11
History Note English:   93; was INTERLEUKIN 11 (NM) 1990-92 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   30682 
Unique Identifier:   D017370 

Occurrence in VHL:
 

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